Order Diltiazem tablets online from a U.S. pharmacy

Product Name	Diltiazem
Dosage	IR: 30 mg, 60 mg, 90 mg, 120 mg; ER: 120 mg, 180 mg, 240 mg, 300 mg, 360 mg, 420 mg (product-dependent)
Active Ingredient	Diltiazem HCl
Form	Immediate-release tablets; extended-release capsules and tablets
Description	Calcium channel blocker for hypertension, chronic stable/vasospastic angina, and rate control in certain supraventricular arrhythmias (e.g., atrial fibrillation/flutter). Rx only in the USA.
How to Purchase	Online pharmacy with valid U.S. prescription or quick telehealth evaluation

Diltiazem is a long-standing cardiovascular medication in the United States, trusted by clinicians for decades to manage high blood pressure, relieve angina symptoms, and help control heart rate in specific supraventricular arrhythmias under medical supervision. It is available in multiple formulations to match individual therapeutic goals and patient preferences. Immediate-release tablets are typically taken several times per day, while extended-release (ER) capsules or tablets are designed for once-daily dosing in many patients.

In the U.S., diltiazem is a prescription medicine. Common brand names include Cardizem, Cardizem CD/LA, Cartia XT, Dilacor XR, Dilt-XR, and Tiazac, among others. High-quality generics are widely available and are often the most cost-effective choice. Through our U.S.-focused online service, patients can request refills with a valid prescription or connect with an independent telehealth provider for an evaluation when appropriate. Orders are shipped quickly and discreetly with tracking to most U.S. addresses.

Diltiazem cost in the USA

The price you pay for diltiazem depends on the formulation (immediate-release vs. extended-release), dosage strength, quantity, manufacturer, and your insurance or discount program. Generic diltiazem is typically far less expensive than brand-name products like Cardizem CD or Tiazac.

As a broad reference: a 30-day supply of generic ER diltiazem (for example, 180 mg once daily) may range from under $15 at certain discount pharmacies to higher amounts at retail chains without coupons. Brand-name versions can be significantly more costly. Our partners frequently offer promotions and price-matching on select strengths to help keep your monthly cost affordable.

Because pricing can change, we recommend checking current offers at checkout. You can also explore multi-month supplies if your prescriber authorizes them; buying a 60- or 90-day supply can sometimes lower the monthly effective price and reduce refills.

Where can I buy diltiazem in the USA?

If your clinician has prescribed diltiazem, you can fill your prescription through our online pharmacy partner and have the medication delivered to your home. If you do not yet have a prescription, you may be able to complete a short telehealth consultation with a licensed U.S. provider to determine whether diltiazem is appropriate for you. Availability of telehealth services varies by state.

We’ve supported U.S. patients for many years by streamlining refills, offering transparent pricing, and providing access to pharmacists who can answer routine medication questions. Orders typically ship within one to two business days after verification by the dispensing pharmacy team.

Prefer to manage everything online? Our platform allows you to track orders, request refills, and message support with ease. This is a convenient option if you’re unable to visit a physical pharmacy, need expedited shipping, or want to compare prices across strengths.

Diltiazem in the United States

Getting diltiazem in the U.S. is straightforward when you have a valid prescription. Choose your preferred dose and quantity, complete checkout, and the pharmacy team will verify your prescription, perform standard safety checks, and process your shipment. If you require a new prescription, a telehealth clinician may review your health history and, if appropriate, issue a prescription electronically to the partner pharmacy.

What is diltiazem?

Diltiazem is a nondihydropyridine calcium channel blocker (non-DHP CCB). It relaxes vascular smooth muscle, reduces heart rate and contractility, and lowers blood pressure. Diltiazem helps improve oxygen delivery to the myocardium and decreases myocardial oxygen demand, making it useful in angina management. Additionally, because of its effects on atrioventricular (AV) nodal conduction, diltiazem can help control ventricular rate in atrial fibrillation or atrial flutter under the direction of a healthcare professional.

Diltiazem is available in immediate-release (IR) tablets taken multiple times daily and in extended-release (ER) capsules or tablets intended for once-daily dosing in many cases. Dosing and formulation choices are individualized based on precise clinical goals, patient response, and tolerability.

Common indications in U.S. clinical practice include:

• Hypertension (high blood pressure)
• Chronic stable angina and vasospastic (Prinzmetal) angina
• Rate control in certain supraventricular arrhythmias (e.g., atrial fibrillation/flutter) as directed by a clinician

Diltiazem for hypertension

For adults with elevated blood pressure, diltiazem can be used alone or in combination with other antihypertensives. Many patients and providers favor extended-release formulations for convenience and smoother 24-hour blood pressure control. Target BP goals follow current U.S. guidelines and are individualized based on age, comorbidities, and cardiovascular risk. Regular monitoring and dose titration help achieve and maintain control.

Diltiazem may be considered particularly in patients who require both blood pressure lowering and heart rate moderation. For others, a dihydropyridine CCB (e.g., amlodipine) or a different class may be preferred. Your prescriber will select a therapy based on your overall profile, comorbid conditions, and possible interactions with current medications.

Diltiazem for angina

Diltiazem relieves angina by dilating coronary arteries, reducing afterload, and decreasing myocardial oxygen demand through heart rate and contractility effects. It is effective in chronic stable angina and vasospastic (Prinzmetal) angina. Patients often notice improved exercise tolerance and reduced frequency of angina episodes after proper titration. Extended-release dosing can simplify regimens and provide steady symptom control throughout the day.

Depending on the clinical picture, diltiazem may be used alone or alongside nitrates, beta blockers (with caution due to additive effects on heart rate and conduction), or statins. Report new or worsening chest pain immediately, and seek urgent care for severe, unusual, or persistent symptoms.

Diltiazem for atrial fibrillation/flutter (rate control)

In atrial fibrillation/flutter, diltiazem can slow AV nodal conduction and help manage ventricular rate. This application is typically overseen by a clinician, especially when starting therapy or adjusting doses. Hospital-based protocols commonly use intravenous diltiazem for acute rate control, followed by transition to oral maintenance regimens. Do not initiate or adjust diltiazem for arrhythmias without guidance from a licensed healthcare professional.

In patients with accessory pathways (e.g., Wolff-Parkinson-White syndrome with atrial fibrillation), non-DHP calcium channel blockers like diltiazem are contraindicated due to the risk of precipitating serious arrhythmias. Your provider will rule out these conditions before prescribing.

How diltiazem works (mechanism of action)

Diltiazem selectively inhibits the influx of calcium ions through L-type calcium channels in cardiac and vascular smooth muscle. The result is peripheral arterial vasodilation (reduced systemic vascular resistance), decreased heart rate and AV nodal conduction, and an overall reduction in myocardial oxygen demand. Compared to dihydropyridine CCBs, non-DHP agents like diltiazem exert more direct cardiac effects, which explains their utility in angina and rate control.

Pharmacokinetics: Diltiazem is extensively metabolized in the liver, primarily by CYP3A4. It has multiple active and inactive metabolites. Extended-release formulations are designed to release drug gradually over 24 hours to maintain smoother plasma levels. Because metabolism occurs in the liver, hepatic impairment can impact clearance. Dose adjustments may be required in certain populations under prescriber supervision.

Diltiazem formulations and strengths

Diltiazem is marketed in multiple dosage forms to match clinical needs:

• Immediate-release tablets: commonly 30 mg, 60 mg, 90 mg, 120 mg (taken 3–4 times daily depending on the regimen)
• Extended-release capsules/tablets: often 120 mg, 180 mg, 240 mg, 300 mg, 360 mg, and 420 mg (once-daily dosing for many brands)
• Intravenous formulations: used under medical supervision for acute arrhythmia rate control in healthcare settings

Note that maximum recommended daily doses differ by product. Always follow the specific dosing instructions for the brand or generic you receive.

How to take diltiazem (adult dosing guidance)

Only use diltiazem under the direction of a licensed prescriber. The following are general examples and may not apply to your case:

• Hypertension (ER products): common starting dose 120–240 mg once daily; adjust every 1–2 weeks. Typical range 120–360 mg daily (up to 420–540 mg for some products as directed by labeling and prescriber judgment).
• Chronic stable/vasospastic angina: IR 30 mg four times daily, titrated gradually; or ER 120–240 mg once daily, titrated to symptom control and tolerability.
• Atrial fibrillation/flutter (rate control): initial IV dosing is determined and administered by medical staff; oral regimens (IR or ER) are individualized for maintenance.

Administration tips:

• Take at the same time each day.
• Swallow extended-release capsules/tablets whole; do not crush or chew. If you have difficulty swallowing, ask your pharmacist about alternative formulations.
• If you miss a dose, take it when you remember unless it is close to your next dose. Do not double doses.
• Monitor blood pressure and heart rate regularly, particularly during initiation and dose adjustments.

Who should not take diltiazem (contraindications)

Do not use diltiazem if you have:

• Hypersensitivity to diltiazem
• Sick sinus syndrome or second-/third-degree AV block without a functioning pacemaker
• Severe hypotension (e.g., systolic BP < 90 mmHg) or cardiogenic shock
• Acute myocardial infarction with pulmonary congestion
• Atrial fibrillation/flutter with accessory bypass tract (e.g., Wolff-Parkinson-White syndrome)

Use with caution in heart failure with reduced ejection fraction due to negative inotropic effects. Your clinician will evaluate risks and benefits.

Safety and monitoring

Diltiazem is generally well tolerated when used as prescribed. Most adverse effects are dose-related and reversible. Your prescriber may periodically check blood pressure, heart rate, and, when indicated, liver function tests or ECGs.

Contact a clinician promptly if you experience significant bradycardia, dizziness or fainting, worsening chest pain, shortness of breath, swelling of the legs, or any symptoms suggestive of an allergic reaction (e.g., hives, facial or throat swelling, difficulty breathing).

Common and possible side effects

Potential adverse reactions may include:

• Peripheral edema (swelling of ankles/feet)
• Bradycardia, palpitations
• Headache, dizziness, fatigue
• Flushing
• Gastrointestinal discomfort, nausea; constipation is less common than with verapamil but can occur
• Rash or pruritus
• Elevations in liver enzymes (rare)
• Gingival hyperplasia with long-term use (infrequent)

This is not a complete list. Side effects vary by dose, formulation, and individual sensitivity. If adverse effects are troublesome, your prescriber may adjust your regimen.

Drug and food interactions

Diltiazem is metabolized primarily by CYP3A4 and can interact with many medications. Inform your prescriber and pharmacist about all prescription and OTC drugs, vitamins, and herbal products you take. Notable interactions include:

• Beta blockers (e.g., metoprolol, propranolol): additive effects on heart rate and AV conduction; monitor for bradycardia or heart block
• Digoxin: diltiazem may increase digoxin levels; monitoring may be required
• Statins metabolized by CYP3A4 (e.g., simvastatin, lovastatin): risk of increased statin exposure; dose limits often apply (e.g., simvastatin typically ≤10 mg/day; lovastatin ≤20 mg/day when used with diltiazem)
• CYP3A4 substrates (e.g., certain immunosuppressants, benzodiazepines, antiarrhythmics): potential increased exposure; dose adjustments/monitoring may be warranted
• CYP3A4 inhibitors/inducers (e.g., strong inhibitors like ketoconazole, clarithromycin; inducers like rifampin): can alter diltiazem levels
• Grapefruit or grapefruit juice: may increase diltiazem concentrations; avoid or limit

Your care team can help manage interactions safely by adjusting therapy, spacing doses, or selecting alternatives.

Diltiazem vs. other calcium channel blockers

Calcium channel blockers are grouped into dihydropyridines (e.g., amlodipine, nifedipine) and nondihydropyridines (diltiazem, verapamil). Dihydropyridines primarily cause peripheral vasodilation with minimal direct cardiac effects, making them excellent antihypertensives. Diltiazem and verapamil affect both vascular smooth muscle and cardiac conduction, offering benefits in angina and rate control but with a greater potential to slow the heart rate. Contraindications and interaction profiles differ; your prescriber will choose the most suitable option.

Pregnancy, breastfeeding, and special populations

Pregnancy: Data in pregnant individuals are limited. Diltiazem should be used during pregnancy only if the potential benefits justify potential risks. Discuss family-planning or pregnancy intentions with your clinician prior to starting therapy.

Breastfeeding: Diltiazem is excreted in human milk. Consider the benefits of breastfeeding, the clinical need for diltiazem, and any potential adverse effects on the infant. Your provider may recommend monitoring or an alternative therapy depending on the clinical scenario.

Older adults: Heightened sensitivity to blood pressure–lowering or heart rate–slowing effects is possible; dose adjustments and careful monitoring may be required.

Hepatic impairment: Diltiazem is metabolized in the liver. Use with caution and consider adjustments under clinician guidance.

Tips from our U.S. pharmacists

Consistency supports the best results. Take diltiazem exactly as prescribed, at the same time each day, and don’t stop suddenly without medical advice. Monitor your blood pressure and heart rate at home if directed, and keep a log to share with your clinician. Report symptoms of slow heartbeat, dizziness, or swelling. If you’re starting any new medications or supplements, ask the pharmacy team about possible interactions first.

Traveling? Bring an updated medication list and enough supply to cover your trip, plus a few extra days. Keep diltiazem in its original container when possible and store it at room temperature away from excess heat and moisture.

Frequently asked questions (FAQ)

Is diltiazem available over the counter in the U.S.? No. Diltiazem is a prescription-only medication in the United States. You will need a valid prescription to purchase it or complete a telehealth evaluation where available.

How long does diltiazem take to work? Some effects, such as reduced heart rate, may be noticeable within hours. Blood pressure and angina improvements are typically assessed over days to weeks as the dose is adjusted.

Can I drink alcohol with diltiazem? Alcohol may enhance blood pressure–lowering effects and increase dizziness. Discuss alcohol intake with your prescriber and use caution, especially when starting or changing doses.

What if I experience swelling in my ankles? Peripheral edema can occur. Elevating your legs, reducing dietary sodium, or dose adjustments may help. Report persistent or severe swelling to your clinician.

Can I take diltiazem with beta blockers? Sometimes, but this combination increases the risk of bradycardia and heart block. Such regimens must be supervised closely.

Storage and handling

Store diltiazem at room temperature (typically 68–77°F / 20–25°C) away from moisture and direct light. Keep the bottle tightly closed and out of reach of children and pets. Do not use medication past its expiration date. If you have unused or expired diltiazem, ask your pharmacist about local take-back programs or safe disposal options.

Insurance, Medicare, and savings

Most U.S. insurance plans and Medicare Part D formularies cover generic diltiazem, often with low copays. Brand-name versions may require higher out-of-pocket costs or prior authorization. If you are uninsured or have a high deductible, discount programs or coupons may reduce your price. Compare costs for different strengths and formulations, as extended-release capsules versus tablets can vary in price and formulary placement.

How online ordering works

Ordering diltiazem through our platform is designed to be simple and secure:

• Select your strength and quantity.
• Upload your prescription or request a telehealth consultation, if available in your state.
• The partner pharmacy verifies your prescription and checks for interactions.
• Orders are dispensed by licensed pharmacists and shipped discreetly with tracking.
• Manage refills and track shipments from your account dashboard.

Pharmacists are available to answer routine questions about dosing, interactions, and side effects. For urgent concerns or serious symptoms, contact your prescriber or emergency services immediately.

Professional guidance and precautions

Diltiazem affects heart rate and conduction. Never start, stop, or change your dose without consulting your prescriber. If you have a history of heart block, heart failure, or conduction abnormalities, your clinician will evaluate whether diltiazem is appropriate. Keep all follow-up appointments and lab checks as recommended.

Summary: Why patients choose diltiazem

Diltiazem’s balanced effects on blood pressure, angina symptoms, and heart rate make it a versatile option for many patients under medical care. With multiple formulations and strengths, dosing can be individualized to fit your routine and clinical needs. When combined with lifestyle measures—such as a heart-healthy diet, regular physical activity, and smoking cessation—diltiazem therapy can be an important part of comprehensive cardiovascular risk reduction.

Recommendations from our U.S. specialists

Our clinical team encourages patients to maintain consistent follow-up and to use home monitoring tools when advised, especially at the beginning of therapy. Keep an updated list of your medications and share it with every healthcare professional you see. If cost is a concern, ask about generic options, dosage optimization, or 90-day supplies to improve affordability and adherence.

Ready to start or refill your diltiazem? Order today

Get genuine, U.S.-dispensed diltiazem delivered securely and discreetly. Whether you’re starting therapy or managing a long-term prescription, we streamline the process so you can focus on your health.

• Prescription support — upload your Rx or request a quick telehealth review where available
• Fast, trackable shipping across the United States
• Authentic medication from licensed U.S. pharmacies
• Competitive prices on generic and brand formulations
• Pharmacist help for dosing, interactions, and refills

Join thousands of U.S. patients who trust our service for reliable, convenient, and affordable refills. Place your order now and stay on track with your cardiovascular care.

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